Review

cm10 sequence lianak (GenScript corporation)

About

News

Press Release

Team

Advisors

Partners

Contact

Bioz Stars

Bioz vStars

Buy from Supplier

Structured Review

GenScript corporation cm10 sequence lianak
List of experimental groups and concentrations evaluated.

Cm10 Sequence Lianak, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cm10 sequence lianak/product/GenScript corporation
Average 90 stars, based on 1 article reviews

cm10 sequence lianak - by Bioz Stars, 2026-06

90/100 stars

Images

1) Product Images from "Comparison of multiple synthetic chondroinductive factors in pellet culture against a TGF-β positive control"

Article Title: Comparison of multiple synthetic chondroinductive factors in pellet culture against a TGF-β positive control

Journal: Osteoarthritis and Cartilage Open

doi: 10.1016/j.ocarto.2023.100369

Figure Legend Snippet: List of experimental groups and concentrations evaluated.

Techniques Used:

Chondrogenic gene expression of ACAN in hBMSCs spheroids after 21 days in culture. No statistically significant differences were observed between groups except for TGF-β3, which had significantly higher aggrecan expression compared to all other groups, including a 10,000-fold larger value compared to the negative control. ∗∗∗∗Refers to significant difference p < 0.0001, n = 6–8. Reported values are mean + standard deviation. SM = SM04690, CK = CK2.1, CM = CM10, CM/CK (100/100) = CM10 at 100 μM and CK2.1 and 100 nM, CM/CK(100/500) = CM10 at 100 μM and CK2.1 and 500 nM, CM/CK (200/100) = CM10 at 200 μM and CK2.1 and 100 nM, CM/CK(200/500) = CM10 at 200 μM and CK2.1 and 500 nM, CM/KGN (100/1) = CM10 at 100 μM and kartogenin at 1 μM, CM/KGN (100/10) = CM10 at 100 μM and kartogenin at 10 μM, CK/KGN (100/1) = CK2.1 at 100 nM and kartogenin at 1 μM, CK/KGN (100/10) = CK2.1 at 100 nM and kartogenin at 10 μM, CM/SM (100/30) = CM10 at 100 μM and SM04690 at 30 nM, CM/SM (100/100) = CM10 at 100 μM and SM04690 at 100 nM, CK/SM (100/30) = CK2.1 at 100 nM and SM04690 at 30 nM, CK/SM (100/100) = CK2.1 at 100 nM and SM04690 at 100 nM.

Figure Legend Snippet: Chondrogenic gene expression of ACAN in hBMSCs spheroids after 21 days in culture. No statistically significant differences were observed between groups except for TGF-β3, which had significantly higher aggrecan expression compared to all other groups, including a 10,000-fold larger value compared to the negative control. ∗∗∗∗Refers to significant difference p < 0.0001, n = 6–8. Reported values are mean + standard deviation. SM = SM04690, CK = CK2.1, CM = CM10, CM/CK (100/100) = CM10 at 100 μM and CK2.1 and 100 nM, CM/CK(100/500) = CM10 at 100 μM and CK2.1 and 500 nM, CM/CK (200/100) = CM10 at 200 μM and CK2.1 and 100 nM, CM/CK(200/500) = CM10 at 200 μM and CK2.1 and 500 nM, CM/KGN (100/1) = CM10 at 100 μM and kartogenin at 1 μM, CM/KGN (100/10) = CM10 at 100 μM and kartogenin at 10 μM, CK/KGN (100/1) = CK2.1 at 100 nM and kartogenin at 1 μM, CK/KGN (100/10) = CK2.1 at 100 nM and kartogenin at 10 μM, CM/SM (100/30) = CM10 at 100 μM and SM04690 at 30 nM, CM/SM (100/100) = CM10 at 100 μM and SM04690 at 100 nM, CK/SM (100/30) = CK2.1 at 100 nM and SM04690 at 30 nM, CK/SM (100/100) = CK2.1 at 100 nM and SM04690 at 100 nM.

Techniques Used: Gene Expression, Expressing, Negative Control

Chondrogenic gene expression of SOX-9 in hBMSCs spheroids after 21 days in culture. No significance was observed between groups except for TGF-β3 with a 50-fold higher gene expression as compared to the negative control. ∗∗∗∗Refers to significant difference p < 0.0001, n = 6–8. Reported values are mean + standard deviation. SM = SM04690, CK = CK2.1, CM = CM10, CM/CK (100/100) = CM10 at 100 μM and CK2.1 and 100 nM, CM/CK(100/500) = CM10 at 100 μM and CK2.1 and 500 nM, CM/CK (200/100) = CM10 at 200 μM and CK2.1 and 100 nM, CM/CK(200/500) = CM10 at 200 μM and CK2.1 and 500 nM, CM/KGN (100/1) = CM10 at 100 μM and kartogenin at 1 μM, CM/KGN (100/10) = CM10 at 100 μM and kartogenin at 10 μM, CK/KGN (100/1) = CK2.1 at 100 nM and kartogenin at 1 μM, CK/KGN (100/10) = CK2.1 at 100 nM and kartogenin at 10 μM, CM/SM (100/30) = CM10 at 100 μM and SM04690 at 30 nM, CM/SM (100/100) = CM10 at 100 μM and SM04690 at 100 nM, CK/SM (100/30) = CK2.1 at 100 nM and SM04690 at 30 nM, CK/SM (100/100) = CK2.1 at 100 nM and SM04690 at 100 nM.

Figure Legend Snippet: Chondrogenic gene expression of SOX-9 in hBMSCs spheroids after 21 days in culture. No significance was observed between groups except for TGF-β3 with a 50-fold higher gene expression as compared to the negative control. ∗∗∗∗Refers to significant difference p < 0.0001, n = 6–8. Reported values are mean + standard deviation. SM = SM04690, CK = CK2.1, CM = CM10, CM/CK (100/100) = CM10 at 100 μM and CK2.1 and 100 nM, CM/CK(100/500) = CM10 at 100 μM and CK2.1 and 500 nM, CM/CK (200/100) = CM10 at 200 μM and CK2.1 and 100 nM, CM/CK(200/500) = CM10 at 200 μM and CK2.1 and 500 nM, CM/KGN (100/1) = CM10 at 100 μM and kartogenin at 1 μM, CM/KGN (100/10) = CM10 at 100 μM and kartogenin at 10 μM, CK/KGN (100/1) = CK2.1 at 100 nM and kartogenin at 1 μM, CK/KGN (100/10) = CK2.1 at 100 nM and kartogenin at 10 μM, CM/SM (100/30) = CM10 at 100 μM and SM04690 at 30 nM, CM/SM (100/100) = CM10 at 100 μM and SM04690 at 100 nM, CK/SM (100/30) = CK2.1 at 100 nM and SM04690 at 30 nM, CK/SM (100/100) = CK2.1 at 100 nM and SM04690 at 100 nM.

Techniques Used: Gene Expression, Negative Control

Gene expression of collagen I of hBMSCs spheroids after 21 days in culture. A variation in the gene expression of collagen I by hBMSCs was observed in response to the evaluated compounds and peptides. CM10 (100 μM) had the highest gene expression with 2.5-fold higher expression compared to the control group. CK2.1 exhibited higher gene expression of collagen I by 1.8 folds and 1.4 folds at 100 nM and 500 nM, respectively. The combination of compounds and peptides did not induce a significant difference in collagen I gene expression as compared to the negative control group. Groups with the same letters indicate no significance, n = 6–8. Reported values are mean + standard deviation. SM = SM04690, CK = CK2.1, CM = CM10, CM/CK (100/100) = CM10 at 100 μM and CK2.1 and 100 nM, CM/CK(100/500) = CM10 at 100 μM and CK2.1 and 500 nM, CM/CK (200/100) = CM10 at 200 μM and CK2.1 and 100 nM, CM/CK(200/500) = CM10 at 200 μM and CK2.1 and 500 nM, CM/KGN (100/1) = CM10 at 100 μM and kartogenin at 1 μM, CM/KGN (100/10) = CM10 at 100 μM and kartogenin at 10 μM, CK/KGN (100/1) = CK2.1 at 100 nM and kartogenin at 1 μM, CK/KGN (100/10) = CK2.1 at 100 nM and kartogenin at 10 μM, CM/SM (100/30) = CM10 at 100 μM and SM04690 at 30 nM, CM/SM (100/100) = CM10 at 100 μM and SM04690 at 100 nM, CK/SM (100/30) = CK2.1 at 100 nM and SM04690 at 30 nM, CK/SM (100/100) = CK2.1 at 100 nM and SM04690 at 100 nM.

Figure Legend Snippet: Gene expression of collagen I of hBMSCs spheroids after 21 days in culture. A variation in the gene expression of collagen I by hBMSCs was observed in response to the evaluated compounds and peptides. CM10 (100 μM) had the highest gene expression with 2.5-fold higher expression compared to the control group. CK2.1 exhibited higher gene expression of collagen I by 1.8 folds and 1.4 folds at 100 nM and 500 nM, respectively. The combination of compounds and peptides did not induce a significant difference in collagen I gene expression as compared to the negative control group. Groups with the same letters indicate no significance, n = 6–8. Reported values are mean + standard deviation. SM = SM04690, CK = CK2.1, CM = CM10, CM/CK (100/100) = CM10 at 100 μM and CK2.1 and 100 nM, CM/CK(100/500) = CM10 at 100 μM and CK2.1 and 500 nM, CM/CK (200/100) = CM10 at 200 μM and CK2.1 and 100 nM, CM/CK(200/500) = CM10 at 200 μM and CK2.1 and 500 nM, CM/KGN (100/1) = CM10 at 100 μM and kartogenin at 1 μM, CM/KGN (100/10) = CM10 at 100 μM and kartogenin at 10 μM, CK/KGN (100/1) = CK2.1 at 100 nM and kartogenin at 1 μM, CK/KGN (100/10) = CK2.1 at 100 nM and kartogenin at 10 μM, CM/SM (100/30) = CM10 at 100 μM and SM04690 at 30 nM, CM/SM (100/100) = CM10 at 100 μM and SM04690 at 100 nM, CK/SM (100/30) = CK2.1 at 100 nM and SM04690 at 30 nM, CK/SM (100/100) = CK2.1 at 100 nM and SM04690 at 100 nM.

Techniques Used: Gene Expression, Expressing, Control, Negative Control

Gene expression of ACAN, SOX-9, and collagen I of hBMSCs spheroids from 3 different donors after 21 days in culture. For ACAN, no statistically significant differences were observed between groups except for TGF-β3 with all donors. Donor-based variation in the gene expression of SOX-9 in response to experimental groups was observed. Notably, CM10 had a significantly higher gene expression of SOX-9 as compared to the negative control only with donor 1 (Female, 20 yrs). SM04690, CM10, and CK2.1 induced a significantly lower gene expression of collagen I as compared to the negative control with all donors, whereas KGN had variable outcomes based on the donor. Groups with the same letters indicate no significance, n = 6–8. Reported values are mean + standard deviation. SM = SM04690, CK = CK2.1, CM = CM10.

Figure Legend Snippet: Gene expression of ACAN, SOX-9, and collagen I of hBMSCs spheroids from 3 different donors after 21 days in culture. For ACAN, no statistically significant differences were observed between groups except for TGF-β3 with all donors. Donor-based variation in the gene expression of SOX-9 in response to experimental groups was observed. Notably, CM10 had a significantly higher gene expression of SOX-9 as compared to the negative control only with donor 1 (Female, 20 yrs). SM04690, CM10, and CK2.1 induced a significantly lower gene expression of collagen I as compared to the negative control with all donors, whereas KGN had variable outcomes based on the donor. Groups with the same letters indicate no significance, n = 6–8. Reported values are mean + standard deviation. SM = SM04690, CK = CK2.1, CM = CM10.

Techniques Used: Gene Expression, Negative Control

Image Search Results

Journal: Osteoarthritis and Cartilage Open

Article Title: Comparison of multiple synthetic chondroinductive factors in pellet culture against a TGF-β positive control

doi: 10.1016/j.ocarto.2023.100369

Figure Lengend Snippet: List of experimental groups and concentrations evaluated.

Article Snippet: For experimental groups, KGN (Cat# HY-16268, MedChemExpress, Monmouth Junction, NJ), SM04690 (Cat# HY-109049, MedChemExpress, Monmouth Junction, NJ), CM10 (Sequence LIANAK, Genscript, New Jersey), and/or CK2.1 (Sequence: QIKIWFQNRRK-WKKMVPSDPSYEDMGGC, Genscript, New Jersey) were added to the control medium at concentrations that were based on the literature and summarized in .

Techniques:

Journal: Osteoarthritis and Cartilage Open

Article Title: Comparison of multiple synthetic chondroinductive factors in pellet culture against a TGF-β positive control

doi: 10.1016/j.ocarto.2023.100369

Figure Lengend Snippet: Chondrogenic gene expression of ACAN in hBMSCs spheroids after 21 days in culture. No statistically significant differences were observed between groups except for TGF-β3, which had significantly higher aggrecan expression compared to all other groups, including a 10,000-fold larger value compared to the negative control. ∗∗∗∗Refers to significant difference p < 0.0001, n = 6–8. Reported values are mean + standard deviation. SM = SM04690, CK = CK2.1, CM = CM10, CM/CK (100/100) = CM10 at 100 μM and CK2.1 and 100 nM, CM/CK(100/500) = CM10 at 100 μM and CK2.1 and 500 nM, CM/CK (200/100) = CM10 at 200 μM and CK2.1 and 100 nM, CM/CK(200/500) = CM10 at 200 μM and CK2.1 and 500 nM, CM/KGN (100/1) = CM10 at 100 μM and kartogenin at 1 μM, CM/KGN (100/10) = CM10 at 100 μM and kartogenin at 10 μM, CK/KGN (100/1) = CK2.1 at 100 nM and kartogenin at 1 μM, CK/KGN (100/10) = CK2.1 at 100 nM and kartogenin at 10 μM, CM/SM (100/30) = CM10 at 100 μM and SM04690 at 30 nM, CM/SM (100/100) = CM10 at 100 μM and SM04690 at 100 nM, CK/SM (100/30) = CK2.1 at 100 nM and SM04690 at 30 nM, CK/SM (100/100) = CK2.1 at 100 nM and SM04690 at 100 nM.

Techniques: Gene Expression, Expressing, Negative Control

Journal: Osteoarthritis and Cartilage Open

Article Title: Comparison of multiple synthetic chondroinductive factors in pellet culture against a TGF-β positive control

doi: 10.1016/j.ocarto.2023.100369

Figure Lengend Snippet: Chondrogenic gene expression of SOX-9 in hBMSCs spheroids after 21 days in culture. No significance was observed between groups except for TGF-β3 with a 50-fold higher gene expression as compared to the negative control. ∗∗∗∗Refers to significant difference p < 0.0001, n = 6–8. Reported values are mean + standard deviation. SM = SM04690, CK = CK2.1, CM = CM10, CM/CK (100/100) = CM10 at 100 μM and CK2.1 and 100 nM, CM/CK(100/500) = CM10 at 100 μM and CK2.1 and 500 nM, CM/CK (200/100) = CM10 at 200 μM and CK2.1 and 100 nM, CM/CK(200/500) = CM10 at 200 μM and CK2.1 and 500 nM, CM/KGN (100/1) = CM10 at 100 μM and kartogenin at 1 μM, CM/KGN (100/10) = CM10 at 100 μM and kartogenin at 10 μM, CK/KGN (100/1) = CK2.1 at 100 nM and kartogenin at 1 μM, CK/KGN (100/10) = CK2.1 at 100 nM and kartogenin at 10 μM, CM/SM (100/30) = CM10 at 100 μM and SM04690 at 30 nM, CM/SM (100/100) = CM10 at 100 μM and SM04690 at 100 nM, CK/SM (100/30) = CK2.1 at 100 nM and SM04690 at 30 nM, CK/SM (100/100) = CK2.1 at 100 nM and SM04690 at 100 nM.

Techniques: Gene Expression, Negative Control

Journal: Osteoarthritis and Cartilage Open

Article Title: Comparison of multiple synthetic chondroinductive factors in pellet culture against a TGF-β positive control

doi: 10.1016/j.ocarto.2023.100369

Figure Lengend Snippet: Gene expression of collagen I of hBMSCs spheroids after 21 days in culture. A variation in the gene expression of collagen I by hBMSCs was observed in response to the evaluated compounds and peptides. CM10 (100 μM) had the highest gene expression with 2.5-fold higher expression compared to the control group. CK2.1 exhibited higher gene expression of collagen I by 1.8 folds and 1.4 folds at 100 nM and 500 nM, respectively. The combination of compounds and peptides did not induce a significant difference in collagen I gene expression as compared to the negative control group. Groups with the same letters indicate no significance, n = 6–8. Reported values are mean + standard deviation. SM = SM04690, CK = CK2.1, CM = CM10, CM/CK (100/100) = CM10 at 100 μM and CK2.1 and 100 nM, CM/CK(100/500) = CM10 at 100 μM and CK2.1 and 500 nM, CM/CK (200/100) = CM10 at 200 μM and CK2.1 and 100 nM, CM/CK(200/500) = CM10 at 200 μM and CK2.1 and 500 nM, CM/KGN (100/1) = CM10 at 100 μM and kartogenin at 1 μM, CM/KGN (100/10) = CM10 at 100 μM and kartogenin at 10 μM, CK/KGN (100/1) = CK2.1 at 100 nM and kartogenin at 1 μM, CK/KGN (100/10) = CK2.1 at 100 nM and kartogenin at 10 μM, CM/SM (100/30) = CM10 at 100 μM and SM04690 at 30 nM, CM/SM (100/100) = CM10 at 100 μM and SM04690 at 100 nM, CK/SM (100/30) = CK2.1 at 100 nM and SM04690 at 30 nM, CK/SM (100/100) = CK2.1 at 100 nM and SM04690 at 100 nM.

Techniques: Gene Expression, Expressing, Control, Negative Control

Journal: Osteoarthritis and Cartilage Open

Article Title: Comparison of multiple synthetic chondroinductive factors in pellet culture against a TGF-β positive control

doi: 10.1016/j.ocarto.2023.100369

Figure Lengend Snippet: Gene expression of ACAN, SOX-9, and collagen I of hBMSCs spheroids from 3 different donors after 21 days in culture. For ACAN, no statistically significant differences were observed between groups except for TGF-β3 with all donors. Donor-based variation in the gene expression of SOX-9 in response to experimental groups was observed. Notably, CM10 had a significantly higher gene expression of SOX-9 as compared to the negative control only with donor 1 (Female, 20 yrs). SM04690, CM10, and CK2.1 induced a significantly lower gene expression of collagen I as compared to the negative control with all donors, whereas KGN had variable outcomes based on the donor. Groups with the same letters indicate no significance, n = 6–8. Reported values are mean + standard deviation. SM = SM04690, CK = CK2.1, CM = CM10.

Techniques: Gene Expression, Negative Control

Review

Structured Review

Images

1) Product Images from "Comparison of multiple synthetic chondroinductive factors in pellet culture against a TGF-β positive control"

Similar Products

Image Search Results